CTRI/2020/11/028876尚未招募不适用
Impact of goal-directed versus liberal fluid therapy on flap outcome in micro vascular free flap reconstructive surgery : a randomised controlled trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- To compare the differences in intraoperative fluid administered for maintaining haemodynamic stability in case and control groups
研究概览
简要总结
Proper restriction of fluid administration during intraoperative period using goal directed fluid therapy strategies would lead to better haemodynamic stability leading to better patient and flap outcome postoperatively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 25.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Nyha class
- •3 Albumin > 2.5 gm/dl Weight 55 kg.
- •100 kg Operation duration > 120 min Blood loss > 1000 ml.
排除标准
- •Cognitive limitations Ejection fraction < 30% Patients with active cardiac dysrhythmia Pulmonary disease expected to prevent 8cc/kg tidal volumes Sleep apnea Renal disease.
结局指标
主要结局
To compare the differences in intraoperative fluid administered for maintaining haemodynamic stability in case and control groups
时间窗: Intraoperative and 48 hours
次要结局
- To check the status of flap outcome post operatively for venous congestion,haematoma evacuation and reanaestomosis(48 hrs)
研究者
研究点 (1)
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