Comparison of two drugs for anaesthesia and duration of pain relief in upper limb surgeries

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2023/05/053047
• Lead Sponsor: Sardar Patel Medical College Associated Group of Hospitals

Brief Summary

In order to prolong the duration of major nerve blocks, several adjuvants have been used such as epinephrine , bicarbonates, opioids, clonidine and neostigmine . There has always been search for ideal adjuvant with lesser side effects. Fentanyl , an opiod agonist, have been used in combination with bupivacaine or ropivacaine to enhance the analgesic efficacy of the drugs and also to facilitate early onset & prolongation of the block effect . There are limited studies comparing the use of ropivacaine with fentanly . Conisdering the minimal side effects and good postoperative analgesic efficacy , We made an attempt to compare the clinical characteristics of Ropivacaine with fentanyl as adjuvant in supraclavicular brachial plexus block among patients undergoing  upper limb surgeries . With the primary aim to compare the efficacy of 0.5 % Ropivacaine and 0.5% Ropivacaine with fentanyl in supraclavicular Brachial Plexus Block in terms of  - (1) Onset of sensory and motor block

(2) Duration and Quality of sensory and motor block (3) Duration of post-operative analgesia & the secondary aim to observe the hemodynamic variables , to observe for side effects & observe surgeons and patients satisfaction .

Detailed Description

Not available

Study Timeline

• Study Start: 2023-02-06
• Last Update Posted: 2023-05-22

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

ASA Physical Status I and II Age : 18-60 years of either sex Patients undergoing elective operative procedures for upper limb surgeries.

Exclusion Criteria

ASA Physical Status> II History of Bleeding diathesis Patients on Anticoagulation therapy Peripheral Neuropathy/Any neurologic disease/ Psychiatric diseases Patients with known history of Respiratory diseases History of Active Liver / Renal diseases/ Chronic Renal Impairment Infection at the site of Block placement Known allergy to the drugs used in the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare the efficacy of 0.5% Ropivcaine and 0.5% Ropivacaine with fenatnyl in Supraclavicular Brachial Plexus Block in terms of -	Till the drug effect is over
Onset of sensory and motor block	Till the drug effect is over
Duration and Quality of sensory and motor block	Till the drug effect is over
Duration of Post operative Analgesia	Till the drug effect is over

Secondary Outcome Measures

Name	Time	Method
To observe the hemodynamic variables ,side effects , surgeon and patient satisfaction scores.	24 hours post operative period

Trial Locations

Locations (1)

Sardar Patel Medical College; 🇮🇳 Bikaner, RAJASTHAN, India

Sardar Patel Medical College

🇮🇳Bikaner, RAJASTHAN, India

T Agalya

Principal investigator

8438445611

agalyaarasu9530@gmail.com