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临床试验/CTRI/2025/02/081146
CTRI/2025/02/081146尚未招募Phase 3 4

Comparative evaluation of post endodontic pain reduction by cryotreated Triphala against conventionally used irrigant in primary teeth

Datta Meghe Institute of Higher Education and Research1 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2025年3月15日最近更新:

试验速览

阶段
Phase 3 4
状态
尚未招募
发起方
入组人数
36
试验地点
1
主要终点
The primary outcome of the study is to access the Effectiveness of cryotherapy and triphala as an intracanal irrigant in reducing post-endodontic pain

研究概览

简要总结

The most widely irrigant currently is sodium hypochlorite, however it has been associated with many adverse effects such as tissue toxicity, shortcoming to remove smear layer, unlikeable taste and smell. Therefore, new material and therapies which could overcome such setbacks have been explored which include cryotherapy and medicinal herbs such as Triphala and Circumin. Cryotherapy has reportedly proven effective in reducing swelling and pain following periodontal surgery, extractions, and implant augmentation, therefore its potential as an intracanal irrigant needs to be explored, eventhough currently it is still a matter of speculation. This study will be implemented at Sharad Pawar Dental College in Wardha, Maharashtra, India in the Department of Paediatric and Preventive Dentistry. A total of 80 primary teeth will be included in the study, which will be divided in 4 Groups( 20 subjects in each group). This study will evaluate and compare the effectiveness of cryotreated triphala with conventionally used normal saline as root canal irrigant for reducing post endodontic pain in primary teeth.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
4.00 Year(s) 至 7.00 Year(s)(—)
性别
All

入选标准

  • symptoms of irreversible pulpitis.
  • Radiographic confirmation of carious lesion nearing or affecting the pulp.
  • At least 2/3rd of the root length present.

排除标准

  • Individuals aged less/ more than age of 4-7 years.
  • uncooperative individuals.

结局指标

主要结局

The primary outcome of the study is to access the Effectiveness of cryotherapy and triphala as an intracanal irrigant in reducing post-endodontic pain

时间窗: Assessment will be done before treatment, immediately after treatment and post 24 hrs

次要结局

未报告次要终点

研究者

发起方
Datta Meghe Institute of Higher Education and Research
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

Arshjot Singh Basra

Datta Meghe Institute of Higher Education and Research

研究点 (1)

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