Detection of Electrocardiographic Brugada Patterns Using High Precordial Leads

• Conditions: Brugada ECG Patterns

• Registration Number: NCT05116488
• Lead Sponsor: Assiut University

Brief Summary

Detection of prevalence of Brugada patterns in our locality in asymptomatic patients , by standard 12 lead ECG level and high precordial ECG level, measuring how much the high precordial leads is more sensitive in Brugada patterns detection than standard level 12 lead ECG in our upper Egyptian population.

Detailed Description

Detection of prevalence of Brugada patterns in our locality in asymptomatic patients , by standard 12 lead ECG level and high precordial ECG level, measuring how much the high precordial leads is more sensitive in Brugada patterns detection than standard level 12 lead ECG in our upper Egyptian population.

The study will include patients fulfilling our criteria presenting to cardiology outpatient clinic and emergency room of Assiut University hospitals.

Study Timeline

• Study First Submitted: 2021-10-16
• Status Verified: 2021-11
• Study First Submitted QC: 2021-11-08
• Last Update Submitted: 2021-11-10
• Study First Posted: 2021-11-11
• Last Update Posted: 2021-11-17
• Study Start: 2021-12-31
• Primary Completion: 2022-12-31
• Study Completion: 2023-12-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

1. patients with IHD,HTN,DM with no organic heart disease by ECHO.
2. healthy persons with normal structure heart by ECHO.

Exclusion Criteria

1. Acute coronary syndrome.
2. cardiomyopathy.
3. severe valvular heart disease.
4. HTN heart disease with LVH.
5. Malignancy.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Detection of electrocardiographic Brugada patterns using high precordial leads positioning among asymptomatic upper Egyptian population	up to 4 hours for each case to make sure of meeting eligibility criteria	Detection of prevalence of Brugada patterns in our locality in asymptomatic patients , by standard 12 lead ECG level and high precordial ECG level, measuring how much the high precordial leads is more sensitive in Brugada patterns detection than standard level 12 lead ECG in our upper Egyptian population.

Secondary Outcome Measures

Name	Time	Method
Follow up of positive cases	six months after diagnosis of Brugada pattern for each case	The positive cases will be educated regarding their condition, asked about their history of syncope and family history of sudden cardiac death and will be educated about avoiding and rapid management of fever and electrolyte disturbances and educated about the list of drugs to be avoided.; The positive cases will be followed up for 6 months both clinically and by Holter at 1st, and 6th month for detection of subclinical ventricular arrhythmias.