Effect of whole grain consumption on inflammatio
Phase 2
- Conditions
- obesity.Obesity due to excess calories
- Registration Number
- IRCT201305191485N10
- Lead Sponsor
- Vice Chancellor for Research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 44
Inclusion Criteria
female; aged 8-15 years; body mass index greater than 85th percentile for age and sex; lack of adherence to a specific diet and the use of medications and supplements and no history of chronic diseases. Exclusion criteria: history of chronic diseases; the use of medications and supplements such as multivitamin mineral supplementation, omega-3 fatty acids, Aspirin, etc in the past 6 months, hormone therapy and alterations in physical activity
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum high sensitive-C Reactive Protein (hs-CRP) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: high sensitive immunoturbidimetry, mg/dL.;Serum Amyloid A (SAA) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?mg/dL.;Serum Inter-Cellular Adhesion Molecule 1 (sICAM-1) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?µg/L.;Serum vascular cell adhesion molecule 1 (sVCAM-1) levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?µg/L.;Serum leptin levels. Timepoint: Week 2, Week 8, Week 12, Week 18. Method of measurement: Enzyme-Linked Immunosorbent Assay (ELISA) ?ng/mL.
- Secondary Outcome Measures
Name Time Method