Evaluation of function of respiratory muscles using a fine wire electrodes under hypoxia, hypercapnia, posture changing, drugs and ventilator.
Not Applicable
- Conditions
- COPD, interstitial pneumonia, neuromuscular disease
- Registration Number
- JPRN-UMIN000018729
- Lead Sponsor
- Kitasato University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- Male
- Target Recruitment
- 7
Inclusion Criteria
Not provided
Exclusion Criteria
Subjects who have history of pulmonary or cardiovascular or neuromuscular disorders were excluded. Subjects who have pointed out some abnormality by pre-study evaluation, including pulmonary function tests, electrocardiography and echocardiography.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method EMG activity of respiratory muscles (i.e. parasternal intercostal, external intercostal, transversus abdominis muscles and so on) obtained by fine wire electrodes.
- Secondary Outcome Measures
Name Time Method Ventilatory parameters (i.e. inspiratory time (TI), expiratory time (TE), total time per breath (TT), frequency of respiration (f), tidal volume (VT) and minute ventilation (VI)), end-tidal CO2 (ETCO2), oxygen saturation values obtained from pulse oximetry (SpO2), and heart rate.