Implementation of Pharmacogenetic Testing in Hospital Wards
- Conditions
- Admitted Multimorbid Patients
- Interventions
- Genetic: Pharmacogenetic testOther: Medication review
- Registration Number
- NCT04573491
- Lead Sponsor
- Hospital Pharmacy Enterprise, South Eastern Norway
- Brief Summary
The purpose of this study is to investigate whether it is feasible to implement pharmacogenetic testing as part of medication review while the patient is admitted to hospital.
- Detailed Description
Earlier studies have shown that pharmacogenetic testing may contribute to optimizing the efficacy of medication treatment and to reduce the risk of adverse effects. Inclusion of pharmacogenetic testing as part of medication reviews reveals more serious drug related problems and leads to more changes in medication treatment than medication review alone.
The use of pharmacogenetic testing as part of medication reviews has not earlier been systematically investigated in hospital patients in Norway. There is little documentation of what is needed to implement the use of pharmacogenetic testing in a hospital ward.
The investigators are conducting a descriptive study in two internal medicine wards at Akershus University Hospital. 50 patients using minimum 5 regular drugs including at least one relevant for pharmacogenetic testing will be enrolled in the study.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 46
- at least 2 long-term conditions
- at least 5 regular drugs of which at least one relevant for pharmacogenetic testing
- at least 2 years life expectancy
- able to communicate in Norwegian
- able to give informed consent
- summary care record
- moderate to severe dementia
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Pharmacogenetic test Pharmacogenetic test Medication review including results from pharmacogenetic testing Pharmacogenetic test Medication review Medication review including results from pharmacogenetic testing
- Primary Outcome Measures
Name Time Method Number of patients with results from pharmacogenetic testing included in medication review from admission to discharge, an average of 1 week Number of patients
- Secondary Outcome Measures
Name Time Method Acceptance of recommendations after medication review and before discharge, an average of 3 days Degree of acceptance of recommendations after pharmacogenetic testing, by prescribers
Documentation of information from pharmacogenetic testing after medication review and before discharge, an average of 3 days Number of patients with information from pharmacogenetic testing documented in the patient journal
Trial Locations
- Locations (1)
Akershus University Hospital
🇳🇴Lørenskog, Nordbyhagen, Norway