NAV-ALI: Effects of Different Levels of Neurally Adjusted Ventilatory Assist (NAVA) in Patients Recovering Spontaneous Breathing After Acute Lung Injury: A Physiological Evaluation.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Acute Lung Injury
- Sponsor
- University Hospital, Caen
- Enrollment
- 15
- Locations
- 1
- Primary Endpoint
- Comparison of physiologic response to varying levels of pressure support and Neurally Adjusted Ventilatory Assist (NAVA)
- Status
- Completed
- Last Updated
- 16 years ago
Overview
Brief Summary
Evaluation of a new ventilatory mode Neurally Adjusted Ventilatory Assist "NAVA" in patients who recover spontaneous breathing after acute lung injury.
Detailed Description
Physiological evaluation of two modes of mechanical ventilation: Neurally Adjusted Ventilatory Assist (NAVA) vs Pressure Support Ventilation, at different levels of ventilator assistance. Evaluation in term of physiological parameters: Tidal volume, Respiratory rate, Inspiratory effort, PaCO2, evaluation of subject-ventilator synchrony. Evaluation of physiological response to varying levels of ventilator assistance.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age \> 18 years
- •Hospitalized in intensive care unit
- •Acute Lung Injury
- •Intubated or tracheotomized and mechanically ventilated
Exclusion Criteria
- •Hemodynamic instability
- •Absence of consent
Outcomes
Primary Outcomes
Comparison of physiologic response to varying levels of pressure support and Neurally Adjusted Ventilatory Assist (NAVA)
Time Frame: 24 hours
Secondary Outcomes
- Subject-ventilator synchrony(24 hours)