Neurally Adjusted Ventilatory Assist (NAVA) in Ventilatory Care of Premature Infants
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- The duration of mechanical ventilation
研究概览
简要总结
The purpose of this study is to find out, whether it is possible to improve the ventilatory care of premature infants by using Neurally adjusted ventilatory assist (NAVA).
The study hypothesis is that by using NAVA-technology and/or by monitoring Edi-signal (the electrical signal of diaphragm), it is possible to accomplish ventilatory care to premature infants more individually.
详细描述
Asynchrony means that the timing of support given by the ventilator is different from patients own breathing pattern. Asynchrony during ventilatory care may increase the risk for complications especially in premature infants with immature lungs.
In this study investigators will compare currently used ventilation methods to a new neurally adjusted ventilatory assist (NAVA). The aim is to find out, whether by using this new method it is possible to decrease the complications associated to ventilatory care and to shorten the need for mechanical ventilation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- — 至 9 Weeks（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All children of postconceptional age from 28+0 to 36+6 weeks needing mechanical ventilation for at least 60 minutes
排除标准
- •severe birth asphyxia, malformations, chromosomal abnormality or other condition, which will decrease the length of life
- •condition which prevents the positioning of an oro-/nasogastric tube
结局指标
主要结局
The duration of mechanical ventilation
时间窗: 1 hour - 6 weeks
次要结局
- Complications associated to mechanical ventilation(1 hour - 6 weeks)