NAV-ALI: Effects of Different Levels of Neurally Adjusted Ventilatory Assist (NAVA) in Patients Recovering Spontaneous Breathing After Acute Lung Injury: A Physiological Evaluation.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Comparison of physiologic response to varying levels of pressure support and Neurally Adjusted Ventilatory Assist (NAVA)
研究概览
简要总结
Evaluation of a new ventilatory mode Neurally Adjusted Ventilatory Assist "NAVA" in patients who recover spontaneous breathing after acute lung injury.
详细描述
Physiological evaluation of two modes of mechanical ventilation: Neurally Adjusted Ventilatory Assist (NAVA) vs Pressure Support Ventilation, at different levels of ventilator assistance.
Evaluation in term of physiological parameters: Tidal volume, Respiratory rate, Inspiratory effort, PaCO2, evaluation of subject-ventilator synchrony.
Evaluation of physiological response to varying levels of ventilator assistance.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Hospitalized in intensive care unit
- •Acute Lung Injury
- •Intubated or tracheotomized and mechanically ventilated
排除标准
- •Hemodynamic instability
- •Absence of consent
研究组 & 干预措施
Pressure Support ventilation
干预措施: PSV - pressure suppot ventilation (Device)
NAVA flow triggering
Spontaneous Breathing using Neurally Adjusted Ventilatory Assist with flow triggering
干预措施: NAVA - Neurally Adjusted Ventilatory Assist (Device)
NAVA EMG triggering
Spontaneous Breathing using Neurally Adjusted Ventilatory Assist with trigger adjusted on diaphragmatic electromyogram
干预措施: NAVA - EMG (Device)
结局指标
主要结局
Comparison of physiologic response to varying levels of pressure support and Neurally Adjusted Ventilatory Assist (NAVA)
时间窗: 24 hours
次要结局
- Subject-ventilator synchrony(24 hours)