The Effect of Opioid-free Anesthesia Using Dexmedetomidine-lidocaine on Acute Postoperative Pain in Gynecological Laparoscopy
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- postoperative pain in recovery room
研究概览
简要总结
The aim of this study is to investigate the effect of opioid-free anesthesia using dexmedetomidine and lidocaine instead of remifentanil infusion, on the acute postoperative pain after the gynecological laparoscopy
详细描述
This study is performed to investigate the effect of dexmedetomidine and lidocaine the postopeative pain, shivering, nausea and vomiting after the gynecological laparoscopy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •patients scheduled for elective gynecological laparoscopy
排除标准
- •emergent surgery
- •cancer surgery
- •chronic pain requiring pain killers
- •psychiatric disease
- •preoperative bradycardia (HR < 50 bpm)
- •allergies
- •pregnancy or breast feeding
研究组 & 干预措施
dexmedetomidine-lidocaine
The study group receives the dexmedetomidine and lidocaine infusion with general anesthesia for gynecological laparoscopy.
干预措施: Dexmedetomidine Hydrochloride (Drug)
dexmedetomidine-lidocaine
The study group receives the dexmedetomidine and lidocaine infusion with general anesthesia for gynecological laparoscopy.
干预措施: Lidocaine Hydrochloride (Drug)
remifentanil
The control group receives the remifentanil infusion with general anesthesia for gynecological laparoscopy
干预措施: Remifentanil Hydrochloride (Drug)
结局指标
主要结局
postoperative pain in recovery room
时间窗: 30 minuetes after the completion of surgery
The pain level is assessed by using NRS (numeric rating scale; 0=no pain , 10=the worst pain)
次要结局
- shivering in recovery room(30 minuetes after the completion of surgery)
- postoperative nausea and vomiting (PONV)(30 minutes after the completion of surgery)
研究者
Young Eun Moon
Associate professor
The Catholic University of Korea