Efficacy and safety of elobixibat in psychiatric disorders patients with chronic constipation -Retrospective observation research- - Efficacy and safety of elobixibat in psychiatric disorders patients with chronic constipation

This study was a retrospective study on effectiveness and safety of elobixibat for chronic constipation in 28 psychiatric outpatients such as depression and schizophrenia. There was a significant increase in frequency of bowel movements per week, 4 and 52 weeks after treatment with elobixibat compared to that before the treatment. In addition, adverse events were observed in 3 patients, although those were not serious including mild diarrhea. (The Japanese Journal of Psychiatry. 2021; 26(6): 553-560)