TCTR20230317007已完成3 期
Efficacy and safety of elobixibat on constipation in end stage kidney disease patients undergoing hemodialysis: a randomized controlled trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 43
研究概览
简要总结
Elobixibat is effective and safe for improving constipation symptoms and LDL in ESKD patients undergoing hemodialysis with chronic constipation
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 Years 至 80 Years（—）
- 性别
- All
入选标准
- •Age >=20 years
- •ESKD on hemodialysis > 3 months
- •Adequate dialysis (spKT/V>1.2)
- •Consistent with the ROME IV criteria for the diagnosis of functional constipation
- •Signed informed consent
排除标准
- •Organic constipation such as mechanical gut obstruction, spinal cord injury
- •Irritable bowel syndrome
- •History of abdominal radiation
- •Medical illness: cancer, cirrhosis, biliary tract obstruction, sepsis
研究者
相似试验
终止
3 期
26 Week Efficacy and Safety Trial for Patients With Chronic Idiopathic ConstipationChronic Idiopathic ConstipationNCT01827592Ferring Pharmaceuticals376
已完成
不适用
Efficacy and safety of elobixibat in psychiatric disorders patients with chronic constipation -Retrospective observation researchPsychiatric disorders patients with chronic constipationJPRN-UMIN000042139agisa clinic28
已完成
不适用
Effects of Elobixibat on rectal visceral perception in constipated patients over 60 years of agechronic constipationJPRN-jRCTs061200030Manabe Noriaki30
已完成
2 期
Efficacy and Safety of Elobixibat in Combination With Cholestyramine for Nonalcoholic Fatty Liver DiseaseNonalcoholic Fatty LiverNonalcoholic SteatohepatitisNCT04235205Yokohama City University102
已完成
不适用
Effects of Elobixibat in patients with diabetes and chronic constipatiopatients with diabetes complicated with chronic constipationJPRN-jRCTs031190092Sone Masakatsu46