To investigate effects and safety of double filtration plasmapheresis(DFPP) on atopic dermatitis and atopic asthma
- Conditions
- Diseases of the blood and blood -forming organs and certain disorders involving the immune mechanism
- Registration Number
- KCT0000357
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 12
The subjects who are 20-65 aged, spontaneously consent this study and put their signature on the consent form, and are relevant below 2 of 3 matters
1) the subjects who have over 10% skin lesion of thier body surfaces or asthma symptoms with dyspnea or coughing disturbing sleeps
2) the subjects who take medications related to atopic dermatits or atopic asthma
3) IgE level > 90
1) severe complications such as liver failure, heart failure, diseases related to blood.
2) pregnant
3)body weight <= 45 kg
4)shock events
5)bleeding tendency
6)steroids sensitive reaction
7)communcation disability
8)recent blood donation
9)complications(such as chronic bronchitis, emphysema and bronchiectasia influencing on therapeutic response
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method score of quality of life ;the number of medications
- Secondary Outcome Measures
Name Time Method SCORAD(SCORing Atopic Dermatitis) index or pulmonary function test index ;immunologic index