Comparison of Two Strategies for Glycemic Control in Acute Ischemic Stroke

Phase 4

• Conditions: Acute Ischemic Stroke
• Interventions: Other: Carbohydrate restrictive strategy; Drug: Intensive insulin therapy

• Registration Number: NCT00747279
• Lead Sponsor: Hospital Sao Domingos

Brief Summary

The purpose of this prospective randomized controlled trial was to compare intensive insulin therapy with a carbohydrate restrictive strategy in patients with acute ischemic stroke evaluating the outcome through the Glasgow Outcome Scale Extended, hospital mortality and NIHSS during the ICU stay.

Detailed Description

Not available

Study Timeline

• Study Start: 2007-06
• Status Verified: 2008-09
• Study First Submitted: 2008-09-04
• Study First Submitted QC: 2008-09-04
• Study First Posted: 2008-09-05
• Last Update Submitted: 2008-09-08
• Last Update Posted: 2008-09-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Adult patients with acute ischemic stroke defined as: Abrupt onset of focal neurologic deficit
• No evidence of intracranial hemorrhage at non-contrasted CT scan.

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Exclusion Criteria

• Age below 18
• Pregnancy

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
1	Carbohydrate restrictive strategy	Carbohydrate restrictive strategy
2	Intensive insulin therapy	Intensive insulin therapy

Primary Outcome Measures

Name	Time	Method
Neurological outcome through the Glasgow Outcome Scale Extended	At least 4 months after hospital discharge

Secondary Outcome Measures

Name	Time	Method
NIHSS during ICU stay	ICU stay
Hospital mortality	Hospital stay

Trial Locations

Locations (1)

Hospital Sao Domingos; 🇧🇷 Sao Luis, MA, Brazil