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Clinical Trials/NCT03109678
NCT03109678
Completed
Not Applicable

A Comparison of the Intubating Laryngeal Mask FASTRACH™ and the Intubating Laryngeal Mask Ambu Aura-i™

Asklepios Kliniken Hamburg GmbH0 sites80 target enrollmentJuly 12, 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Airway Management
Sponsor
Asklepios Kliniken Hamburg GmbH
Enrollment
80
Primary Endpoint
success rate of blind intubation
Status
Completed
Last Updated
9 years ago

Overview

Brief Summary

The intubating laryngeal mask Fastrach™ is considered a gold standard for blind intubation as well as for fibreoptic guided intubation via a laryngeal mask. Recently, a single use version of the mask has been introduced. The Fastrach single use laryngeal mask is beng compared to the new, low-priced single use intubating laryngeal mask Ambu Aura-i™.

Detailed Description

Eighty patients undergoing general anaesthesia with planned tracheal intubation for elective surgical procedures are enrolled in the study after checking for inclusion and exclusion criteria. Patients are randomised to either LMA group for blind tracheal intubation with either a standard PVC tracheal tube, or a specifically for the LMA Fastrach developed tube, yielding 4 subgroups. After a standardised anaesthesia induction, blind intubation is performed in each study group. Different time intervals are documented, such as time to first adequate lung ventilation, or f.e. time for laryngeal mask placement. A crossover-design is performed after unsuccessful intubation, using the alternate LMA or the other tracheal tube. LMA placement is visualised by fibreoptic control. An estimated success rate for blind intubation of 60% in the Aura-i group versus 90% in the Fastrach group yields a sample size of n= 38. To compensate for dropouts, n=40 subjects are enrolled in each group.

Registry
clinicaltrials.gov
Start Date
July 12, 2011
End Date
March 7, 2012
Last Updated
9 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dr. Robert Schiewe

Doctor

Asklepios Kliniken Hamburg GmbH

Eligibility Criteria

Inclusion Criteria

  • patients undergoing planned general anaesthesia
  • planned tracheal intubation
  • elective surgical procedure
  • 15 to 80 years of age

Exclusion Criteria

  • ASA physical status IV and V
  • severe pulmonary comorbidity (COPD GOLD \>III, bronchial asthma)
  • indication for rapid-sequence induction
  • mouth opening (interincisor distance) \<3cm
  • morbid obesity (BMI \>35kg.m-2)

Outcomes

Primary Outcomes

success rate of blind intubation

Time Frame: through study completion; time frame for individual study patient: two attempts of blind tracheal intubation peri-interventional, time maximum of 300 seconds

overall success rate of blind tracheal intubation within two attempts using either the FASTRACH™ laryngeal mask or the Ambu Aura-i™ laryngeal mask

Secondary Outcomes

  • subjective handling score(through study completion; the handling of the laryngeal masks during the first placement attempt within 60 seconds; directly after placing laryngeal masks and before fibreoptic visualisation, the subjective handling score is documented as above)
  • influence of tracheal tubes(through study completion; time frame for individual study patient: two attempts of blind tracheal intubation peri-interventional, time maximum of 300 seconds)
  • equivalence of the laryngeal masks regarding fibreoptic visualisation(through study completion; after placing the laryngeal mask and checking for airway leak pressure, fibreoptic visualisation is performed within 60 seconds)
  • differences in airway leak pressure(through study completion; right after placing the laryngeal mask and checking for correct positioning, ALP is documented within 60 seconds)
  • incidence of postoperative sore throat and hoarseness(patient interview 24 hours post procedural)

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