Cohort Study of Chronic Heart Failure
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20,000
- 主要终点
- cardiac marker
研究概览
简要总结
The purpose is to understand the clinical characteristics of chronic heart failure as soon as possible, analyze the etiology, comorbidities, clinical characteristics, and treatment of heart failure patients, observe the gap between real-world clinical practice and guideline recommendations, and provide reference for the improvement of heart failure prevention and treatment in China.
详细描述
Inclusion criteria:
- Accompanied by difficulty breathing, fatigue, or decreased activity tolerance;
- Signs of fluid retention (pulmonary congestion and peripheral edema);
- Echocardiography shows abnormalities in cardiac structure and/or function;
- Elevated levels of natriuretic peptide: B-type natriuretic peptide (BNP)>35 ng/L and/or N-terminal B-type proBNP (NT proBNP)>125 ng/L.
- HF hospitalization recorded within the previous 12 months
Exclusion criteria:
- Concomitant severe liver function, renal failure, or other severe system dysfunction
- Poor compliance, inability to obtain information, or voluntary refusal to participate in this study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 19 Years 至 99 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Accompanied by difficulty breathing, fatigue, or decreased activity tolerance;
- •Signs of fluid retention (pulmonary congestion and peripheral edema);
- •Echocardiography shows abnormalities in cardiac structure and/or function;
- •Elevated levels of natriuretic peptide: B-type natriuretic peptide (BNP)>35 ng/L and/or N-terminal B-type proBNP (NT proBNP)>125 ng/L.
排除标准
- •Concomitant severe liver function, renal failure, or other severe system dysfunction
- •Poor compliance, inability to obtain information, or voluntary refusal to participate in this study.
结局指标
主要结局
cardiac marker
时间窗: Follow up will be conducted at baseline, 6 months, 12 months, and 36 months
CK，CK-MB，cTnT，cTnI，Mb
serum biochemical indicators
时间窗: Follow up will be conducted at baseline, 6 months, 12 months, and 36 months
HDL-cholesterol, mg/dL，LDL-cholesterol, mg/dL，Total cholesterol, mg/dL，Triglycerides, mg/dL
echocardiogram
时间窗: Follow up will be conducted at baseline, 6 months, 12 months, and 36 months
ejection fraction,Consider heart failure when the ejection fraction is less than 50%
次要结局
- Thyroid Function(Follow up will be conducted at baseline, 6 months, 12 months, and 36 months)
- Coagulation function indicators(Follow up will be conducted at baseline, 6 months, 12 months, and 36 months)
- Blood routine(Follow up will be conducted at baseline, 6 months, 12 months, and 36 months)
研究者
Xiang Xie
professor
Xinjiang Medical University