Comparative Evaluation of the Efficacy of Intraoral Cryotherapy Versus Intracanal Cryotherapy on Postoperative Pain

Not Applicable

• Conditions: Postoperative Pain
• Interventions: Procedure: Intraoral Cryotherapy; Procedure: Intracanal Cryotherapy

• Registration Number: NCT05041738
• Lead Sponsor: Cairo University

Brief Summary

The aim of this study is to clinically compare the efficacy of intraoral cryotherapy versus intracanal cryotherapy after single visit root canal therapy in lower molars with irreversible pulpitis and symptomatic apical periodontitis

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-09
• Study First Submitted: 2021-09-08
• Study First Submitted QC: 2021-09-08
• Last Update Submitted: 2021-09-08
• Study First Posted: 2021-09-13
• Last Update Posted: 2021-09-13
• Study Start: 2021-10-01
• Primary Completion: 2022-10-01
• Study Completion: 2022-10-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 68

Inclusion Criteria

Systemically healthy patient (ASA I or II).

Mandibular first molar teeth with:

• Preoperative sharp pain and symptomatic apical periodontitis
• Absence or slight widening in the periodontal ligament (PDL).
• Vital response of pulp tissue to cold pulp tester (ethyl chloride spray) .
• Positive response to percussion test

Exclusion Criteria

1. Medically compromised patients.
2. Pregnant women.
3. Patients reporting bruxism or clenching.
4. Patients allergic to ciprofloxacin or metronidazole.
5. Teeth associated with acute periapical abscess and/or swelling.
6. Greater than grade I mobility or pocket depth greater than 5mm.
7. Size of periapical radiolucency is greater than 8 mm.
8. No restorability: Hopeless tooth.
9. Immature teeth.
10. Radiographic evidence of external or internal root resorption vertical root fracture, perforation, calcification.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intraoral Cryotherapy	Intraoral Cryotherapy	-
Intracanal Cryotherapy	Intracanal Cryotherapy	-

Primary Outcome Measures

Name	Time	Method
Postoperative pain assessed using Visual Analogue scale	24 hours post treatment	Intensity of pain after root canal treatment will be recorded by the patient where "0= no pain, 1-3= mild pain, 4-6= moderate pain, 7-10= severe pain."

Secondary Outcome Measures

Name	Time	Method
Postoperative pain assessed using Visual Analogue scale	72 hours post treatment	Intensity of pain after root canal treatment will be recorded by the patient where "0= no pain, 1-3= mild pain, 4-6= moderate pain, 7-10= severe pain."