NCT01455298已完成不适用
Research of Infra Clinical Liver Injuries in Adult Patients Presented With Alpha-1 AT Deficiency
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 2
- 主要终点
- The prevalence of infra clinical liver injuries
研究概览
简要总结
This cohort study will evaluate the prevalence of the infra clinical liver injuries among a group of adult patients presenting with Alpha-1 AT deficiency followed up in a large university hospital in Lyon, France.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over 18 years old
- •Presenting an Alpha-1 AT deficiency (Alpha-1 AT level <0.8g/l at the time of diagnosis)
排除标准
- •Patients presenting a liver disease not related to the Alpha-1 AT deficiency
研究组 & 干预措施
Transient elastography and fibrotest
Other
干预措施: Transient Elastography and fibrotest (Other)
结局指标
主要结局
The prevalence of infra clinical liver injuries
时间窗: At least one day depending on the schedule of the exams
The prevalence of infra clinical liver injuries (lesions or liver abnormalities) in a cohort of adult patients presenting an Alpha-1 AT deficiency. Suspicion of fibrosis was defined as liver stiffness \> 7.2kPa measured by transient elastography (TE).
次要结局
- morphological liver complications description(At least one day depending on the schedule of the exams)
- measure of biological parameters(At least one day depending on the schedule of the exams)
研究者
研究点 (2)
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