Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of Intraoperative Incision Wound in Preventing Surgical Site Infections in Emergency Laparotomies: A Randomized Controlled Trial
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- Incidence of Superficial Surgical site infections
研究概览
简要总结
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are:
- Incidence of SSI after intervention
- Length of hospital stay
Participants will be randomly assigned to two groups receiving either of the two groups:
Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation.
Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi
- •The age of patients should be between 18-60 years old.
排除标准
- •Diabetic patients
- •Immune-suppressed patients
- •Patients taking steroids
- •Patients undergoing chemo-radiotherapy.
- •Pregnant females
- •Previous abdominal surgery within the last 30 days.
- •Presence of concurrent abdominal wall infections.
- •Trauma Laparotomies
- •Large Bowel perforations
结局指标
主要结局
Incidence of Superficial Surgical site infections
时间窗: Upto 4 weeks post-operatively
Development of Superficial Surgical Site Infection as determined by the CDC guidelines.
次要结局
- Length of Hospital Stay(Upto 4 weeks post-operatively)
研究者
Omer bin khalid
Principal Investigator (Assistant Professor)
Dow University of Health Sciences