Effects of tDCS on Anaerobic Power of Lower Limb Muscles

Phase 2

Completed

• Conditions: Healthy Volunteers
• Interventions: Device: Transcranial direct current stimulation

• Registration Number: NCT04467476
• Lead Sponsor: Universidade Federal do Piauí

Brief Summary

Anaerobic power and capacity are essential in many human activities, especially during sports practice that demand a high strength and power of the limbs. Transcranial direct current stimulation is a noninvasive technique that can modulate motor brain areas involved in motor functions and has the potential to optimize muscle capacity. However, their effects on mechanical power are lacking.

This study aims to investigate the effects of transcranial direct current stimulation (tDCS) on mechanical power in healthy subjects.

Detailed Description

In this study, a randomized, crossover, double-blind, placebo-controlled experimental design will be used. The 50 participants will be randomized into two groups: (1) Anodal tDCS(real) and (2) Sham tDCS. A single session of anodal and sham tDCS will be performed on each task (pre and post-jump test).

All evaluations will be performed by a single researcher who, like the participants, will not know which stimulation group will be participating. Subjects who agree to the conditions and sign the consent form may participate in the study. Participants who meet the eligibility criteria will be included in the study.

Study Timeline

• Study First Submitted: 2020-07-07
• Study First Submitted QC: 2020-07-09
• Study First Posted: 2020-07-13
• Study Start: 2021-01-01
• Primary Completion: 2021-02-28
• Status Verified: 2021-04
• Study Completion: 2021-04-29
• Last Update Submitted: 2021-04-29
• Last Update Posted: 2021-05-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Healthy subjects with no complaints of pain or any kind of discomfort in the musculoskeletal system

Exclusion Criteria

• Musculoskeletal or neurological disorder
• Under medication
• Previous treatment with tDCS

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
tDCS (anodal)	Transcranial direct current stimulation	tDCS: 20 minutes, 2mA, over the motor cortex representation of lower limbs.
tDCS (sham)	Transcranial direct current stimulation	tDCS: 20 minutes (but 30s ON), 2mA, over the motor cortex representation of lower limbs.

Primary Outcome Measures

Name	Time	Method
Mean anaerobic power	Pre and Post-test (immediately after tDCS)	Mean anaerobic power will be evaluated by assessing the ground reaction forces (GRF) and the number of jumps in each test by means of the kinetic analysis of the 60-second vertical jump test (Bosco's Test).

Secondary Outcome Measures

Name	Time	Method
Fatigue index	Pre and Post-test (immediately after tDCS)	Fatigue index will be evaluated by assessing the ground reaction forces (GRF) and the number of jumps in each test by means of the kinetic analysis of the 60-second vertical jump test (Bosco's Test).; The fatigue index corresponds to the power reduction rate expressed as a percentage and reveals the degree of reduction in the ability to produce strength and maintain exercise.
Peak anaerobic power	Pre and Post-test (immediately after tDCS)	Peak anaerobic power will be evaluated by assessing the ground reaction forces (GRF) and the number of jumps in each test by means of the kinetic analysis of the 60-second vertical jump test (Bosco's Test).
Rating of perceived exertion	Post-test (immediately after tDCS)	The subjective feeling of effort will be assessed by the Borg scale for perceived effort. This is a 15-point numerical scale that ranges from 6 to 20, where 6 means "no exertion at all" and 20 means "maximal exertion."

Trial Locations

Locations (1)

Department of Physical Therapy. Federal University of Piaui; 🇧🇷 Parnaíba, Piauí, Brazil