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Clinical Trials/NCT01095068
NCT01095068
Terminated
Not Applicable

Beneficial Effects of Exercise Training on Physical Capacity in Type 2 Diabetics: Improvement in Skeletal Muscle Energetic Capacity, Endothelial Dysfunction and Glycemic Control

University Hospital, Strasbourg, France3 sites in 1 country15 target enrollmentMarch 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Type 2 Diabetes Mellitus
Sponsor
University Hospital, Strasbourg, France
Enrollment
15
Locations
3
Status
Terminated
Last Updated
8 years ago

Overview

Brief Summary

The aim of this study is to evaluate the improvement in skeletal muscle energetic capacity, endothelial dysfunction and glycemic control induced by physical training in 20 sedentary patients with a type 2 diabetes.The protocol consists in a physical training program with 3 sessions of 30 minutes per week during six consecutive weeks. A skeletal muscle biopsy, a cardiac and humeral artery ultrasounds, a glycemic and tensional holters will be performed before and at the end of the physical training program.

Registry
clinicaltrials.gov
Start Date
March 2010
End Date
August 2014
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
University Hospital, Strasbourg, France
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • sedentary adult with type 2 diabetes
  • BMI between 25 and 35 kg/m²
  • Hba1c \< 10 %

Exclusion Criteria

  • unstable coronary artery disease
  • advanced peripheral occlusive arterial disease
  • proteinuria \> 3 g/d and / or creatinine clearance \< 30 ml / mn
  • advanced diabetic neuropathy

Outcomes

Primary Outcomes

Not specified

Study Sites (3)

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