The Efficacy of Baclofen to Treat Gastroesophageal Reflux disease in Children Aged 6 Months to 12 Years
- Conditions
- Gastroesophageal Reflux symptom
- Registration Number
- TCTR20200415001
- Lead Sponsor
- Golestan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 62
all children aged 6 months to 12 years with GERD who had at least two of the following five symptoms for at least one month. These symptoms included vomiting immediately after feeding, the persistence of reflux symptoms despite other treatments, restlessness after feeding for one to three hours, apnea and respiratory distress after feeding, no weight gain or weight gain of less than 500 grams, or weight loss during the last month and refusal to feed
patients less than 6 months and more than 12 years, patients taking baclofen for reasons other than GERD, patients with a history of anti-reflux surgery, patients with endoscopic evidence of Helicobacter pylori gastritis or eosinophilic esophagitis, patients with evidence of gastroparesis radiography and lack of parental consent to participate in the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gastroesophageal Reflux disease 4 month clinical symptoms of the patients
- Secondary Outcome Measures
Name Time Method Gastroesophageal Reflux disease 4 month abdominal pain, nausea, retrosternal pain, weight loss, poor appetite, dyspepsia, regurgitation, cou