Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge

Not Applicable

• Conditions: Alveolar Bone Resorption; Bone Resorption; Alveolar Bone Loss; Bone Graft Failure

• Registration Number: NCT03584984
• Lead Sponsor: Cairo University

Brief Summary

Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6 mm). Alveolar socket preservation is thought to deal with this issue as to prevent the loss of alveolar bone dimensions post extraction in the case of delayed implant placement

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-06-29
• Status Verified: 2018-07
• Study First Submitted QC: 2018-07-11
• Study First Posted: 2018-07-12
• Last Update Submitted: 2018-07-13
• Last Update Posted: 2018-07-17
• Study Start: 2018-08-01
• Primary Completion: 2019-01-01
• Study Completion: 2019-07-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation.
• Both sexes.
• No intraoral soft and hard tissue pathology.
• No systemic condition that contraindicate implant placement.

Exclusion Criteria

• Presence of fenestrations or dehiscence of the residual bony Walls after extraction.
• Heavy smokers more than 20 cigarettes per day .(24)
• Patients with systemic disease that may affect normal healing.
• Psychiatric problems
• Disorders to implant are related to a history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site.
• Patients that refuse to be called back for implant placement post extraction.
• Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration.
• Pregnant Females.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Histomorphometrical bone analysis	6 month post primary surgery	histological bone core analysis

Secondary Outcome Measures

Name	Time	Method
Alveolar Bone marginal loss	6 month post primary surgery	CBCT measurements of marginal bone dimensional difference