Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge
Not Applicable
- Conditions
- Alveolar Bone ResorptionBone ResorptionAlveolar Bone LossBone Graft Failure
- Interventions
- Procedure: Anorganic Bovine Bone (ABB)Procedure: Absorbable gelatin spongeProcedure: Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)
- Registration Number
- NCT03584984
- Lead Sponsor
- Cairo University
- Brief Summary
Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6 mm). Alveolar socket preservation is thought to deal with this issue as to prevent the loss of alveolar bone dimensions post extraction in the case of delayed implant placement
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
- Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation.
- Both sexes.
- No intraoral soft and hard tissue pathology.
- No systemic condition that contraindicate implant placement.
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Exclusion Criteria
- Presence of fenestrations or dehiscence of the residual bony Walls after extraction.
- Heavy smokers more than 20 cigarettes per day .(24)
- Patients with systemic disease that may affect normal healing.
- Psychiatric problems
- Disorders to implant are related to a history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site.
- Patients that refuse to be called back for implant placement post extraction.
- Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration.
- Pregnant Females.
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Anorganic bovine bone graft (ABB) Anorganic Bovine Bone (ABB) filling the extraction socket with ABB graft Absorbable gelatin Sponge Absorbable gelatin sponge Filling the socket with an absorbable gelatin sponge Mixture of Autogenous bone & Anorganic Bovine Bone (ABB) Mixture of Autogenous bone & Anorganic Bovine Bone (ABB) socket preservation with a mixture of autogenous bone graft acquired at the time of extraction mixed with a 50:50 ratio of Anorganic bovine bone
- Primary Outcome Measures
Name Time Method Histomorphometrical bone analysis 6 month post primary surgery histological bone core analysis
- Secondary Outcome Measures
Name Time Method Alveolar Bone marginal loss 6 month post primary surgery CBCT measurements of marginal bone dimensional difference