MedPath

Autogenous Bone Mixed With Xenograft Versus Xenograft Alone Versus Absorbent Gelatin Sponge

Not Applicable
Conditions
Alveolar Bone Resorption
Bone Resorption
Alveolar Bone Loss
Bone Graft Failure
Interventions
Procedure: Anorganic Bovine Bone (ABB)
Procedure: Absorbable gelatin sponge
Procedure: Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)
Registration Number
NCT03584984
Lead Sponsor
Cairo University
Brief Summary

Alveolar bone atrophy post-extraction has been well documented in the past years. normal healing event results in a minimal loss of vertical height (around 1 mm), but a substantial loss of width in the buccal-lingual plane (4-6 mm). Alveolar socket preservation is thought to deal with this issue as to prevent the loss of alveolar bone dimensions post extraction in the case of delayed implant placement

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
30
Inclusion Criteria
  • Adult patients with hopeless mandibular molars indicated for extraction and implant placement in two stages that indicate socket preservation.
  • Both sexes.
  • No intraoral soft and hard tissue pathology.
  • No systemic condition that contraindicate implant placement.
Read More
Exclusion Criteria
  • Presence of fenestrations or dehiscence of the residual bony Walls after extraction.
  • Heavy smokers more than 20 cigarettes per day .(24)
  • Patients with systemic disease that may affect normal healing.
  • Psychiatric problems
  • Disorders to implant are related to a history of radiation therapy to the head and neck neoplasia, or bone augmentation to implant site.
  • Patients that refuse to be called back for implant placement post extraction.
  • Patients that have exceeded bone resorption surrounding the tooth prior to extraction and require guided bone regeneration.
  • Pregnant Females.
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Anorganic bovine bone graft (ABB)Anorganic Bovine Bone (ABB)filling the extraction socket with ABB graft
Absorbable gelatin SpongeAbsorbable gelatin spongeFilling the socket with an absorbable gelatin sponge
Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)Mixture of Autogenous bone & Anorganic Bovine Bone (ABB)socket preservation with a mixture of autogenous bone graft acquired at the time of extraction mixed with a 50:50 ratio of Anorganic bovine bone
Primary Outcome Measures
NameTimeMethod
Histomorphometrical bone analysis6 month post primary surgery

histological bone core analysis

Secondary Outcome Measures
NameTimeMethod
Alveolar Bone marginal loss6 month post primary surgery

CBCT measurements of marginal bone dimensional difference

© Copyright 2025. All Rights Reserved by MedPath