Advancing addiction treatment
- Conditions
- alcohol addiction / alcohol verslavingrepetitive Transcranial Magnetic Stimulation (rTMS) / repetitieve Transcraniële Magnetische Stimulatietreatment / behandelingfunctional Magnetic Resonance Imaging (fMRI)
- Registration Number
- NL-OMON22620
- Lead Sponsor
- AMC, department of psychiatry, Addiction care
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Other
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
Men and women.
- Age between 25-65.
Exclusion Criteria
- A DSM-V diagnosis of schizophrenia or another psychotic disorder, personality disorder or sleep disorder.
- TMS contraindications: history of epileptic seizures or epilepsy in a first degree relative, irregular sleep/ wake rhythm.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The total number of abstinent days at six months follow up: <br>See Schluter, R. S., van Holst, R. J., & Goudriaan, A. E. (2018). Repetitive transcranial magnetic stimulation (rTMS) in alcohol dependence: study protocol of a randomized controlled clinical trial of efficacy and working mechanisms. BMC psychiatry, 18(1), 1-12.
- Secondary Outcome Measures
Name Time Method Secondary outcomes are changes in craving (immediately after 2-week rTMS treatment; at 3-months and at 6-months and 12-months past treatment; changes in SST, AAT (cognitive tasks), and changes in (f)MRI measures immediately after rTMS treatment