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Transcranial direct current stimulation and scalp electroacupuncture on cortical plasticity in healthy individuals

Phase 1
Completed
Conditions
Healthy Subjects
Registration Number
ITMCTR1900002620
Lead Sponsor
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine affiliated to Shanghai University of Traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

(1) Aged 20-30 years old;
(2) The subjects had no history of nervous system disease, heart disease and epilepsy;
(3) Right-handed;
(4) Good physical and mental health;
(5) Sleep quality is normal;
(6) Sign the informed consent.

Exclusion Criteria

(1) Local skin infections, ulcers, scars, hemorrhagic tendencies, severe hemorrhagic diseases and coagulation disorders were found in subjects who were over-sensitive to acupuncture.
(2) Psychiatric history such as mood disorder, depression and mania, epilepsy or seizure history, first-degree relatives have epilepsy history, and those with severe mental illness or accompanying mental symptoms.
(3) Those with metal implants, magnetic resonance imaging or transcranial magnetic contraindications in the body.
(4) Recurrent headache with unknown causes and ineffective drug treatment; skull fracture and/or severe head injury; head and/or brain surgery history.
(5) They are taking tricyclic antidepressants, psychotropic tranquilizers or other drugs to control seizures.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Transcranial magnetic stimulation motor evoked potential (TMS-MEP);
Secondary Outcome Measures
NameTimeMethod
Magnetic resonance imaging;
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