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The Neurobiological Foundations of Treatment Response in Children with Developmental Dyslexia: An exploratory study

Completed
Conditions
Reading Disorder
eerstoornis
Dyslexia
Registration Number
NL-OMON42443
Lead Sponsor
Radboud Universiteit Nijmegen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
41
Inclusion Criteria

Dyslexic children
- 11-13 years of age
- Children with dyslexia must have completed a DD treatment program according to the Dutch nationally standardized protocol (see Blomert, 2006)
- Speak Dutch as their first language
Control group
- 11-13 years of age or
- 8-10 years of age
- No diagnosis of dyslexia
- Speak Dutch as their first language

Exclusion Criteria

- The participant has developmental dyslexia, but has not (yet) finished a DD treatment program.
- Significant hearing or visual impairments not correctable by glasses or hearing aids
- Any MRI counter-indications (e.g., metal implants, braces)

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>In the proposed study, brain activation patterns and structural measures of the<br /><br>connectivity of the brain are the dependent variables. We are particularly<br /><br>interested in the neural correlates of treatment response and whether and how<br /><br>this resembles or differs from age- and reading matched controls. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>On a behavioural level, we will measure reading accuracy and fluency,<br /><br>phonological awareness capacity, and response to online altered auditory<br /><br>feedback (as a measure of speech perception/production interactions). </p><br>
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