The Neurobiological Foundations of Treatment Response in Children with Developmental Dyslexia: An exploratory study
- Conditions
- Reading DisordereerstoornisDyslexia
- Registration Number
- NL-OMON42443
- Lead Sponsor
- Radboud Universiteit Nijmegen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 41
Dyslexic children
- 11-13 years of age
- Children with dyslexia must have completed a DD treatment program according to the Dutch nationally standardized protocol (see Blomert, 2006)
- Speak Dutch as their first language
Control group
- 11-13 years of age or
- 8-10 years of age
- No diagnosis of dyslexia
- Speak Dutch as their first language
- The participant has developmental dyslexia, but has not (yet) finished a DD treatment program.
- Significant hearing or visual impairments not correctable by glasses or hearing aids
- Any MRI counter-indications (e.g., metal implants, braces)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>In the proposed study, brain activation patterns and structural measures of the<br /><br>connectivity of the brain are the dependent variables. We are particularly<br /><br>interested in the neural correlates of treatment response and whether and how<br /><br>this resembles or differs from age- and reading matched controls. </p><br>
- Secondary Outcome Measures
Name Time Method <p>On a behavioural level, we will measure reading accuracy and fluency,<br /><br>phonological awareness capacity, and response to online altered auditory<br /><br>feedback (as a measure of speech perception/production interactions). </p><br>