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临床试验/NCT06648603
NCT06648603已完成不适用

Citizen Action for Sustainable Dengue Control in Sub-Saharan Africa

Swiss Tropical & Public Health Institute1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年7月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
Aedes aegypti mean number per trap per day

研究概览

简要总结

This project focuses on addressing arboviral outbreaks in Ivory Coast by involving local communities in the sustainable control of Aedes mosquitoes, utilizing scientific advice and environmental interventions. It will evaluate the impact of a participatory strategy on decreasing mosquito populations and the risk of virus transmission, aiming to provide insights for policy development on disease prevention.

详细描述

This project targets the growing threat of Aedes mosquito-borne diseases such as dengue in Africa, focusing on the Anono and Gbagba communities in Abidjan, Ivory Coast, by transitioning from traditional control approaches to a community-driven strategy. It focuses on educating and involving communities in the design of sustainable mosquito management measures, such as breeding site eradication and adult mosquito capturing, with scientific experts guiding the efforts. The approach will entail conducting sociocultural surveys and interactive workshops while also encouraging local participation and multi-sectoral collaboration. A randomized controlled trial (RCT) will test this effectiveness of this novel integrated community-based participatory intervention approach in reducing the transmission of Aedes mosquito and other arboviruses. This effort seeks to develop a scalable model for arboviral disease control, promote community resilience, and inform policy recommendations for better public health outcomes in resource-constrained urban settings.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Prevention
盲法
Single (Outcomes Assessor)

盲法说明

Statistician unaware of the arms allocation

入排标准

性别
All
接受健康志愿者

入选标准

  • 未提供

排除标准

  • Outside of trial clusters: households located outside the designated clusters in the two districts were excluded.
  • Refusal to participate: households that do not consent to mosquito trap placement or surveys
  • Inaccessibility: households that are not accessible for regular visits or data collection (e.g., due to relocation or difficult terrain).

结局指标

主要结局

Aedes aegypti mean number per trap per day

时间窗: Continuously during months 1-4 (baseline) and months 5-17 (trial)

Biting rate is the mean number of Aedes females per trap and per day. The proportion of unfed, fed, half-gravid and gravid females will be estimated.

次要结局

  • House index(Before (month 1), twice during (month 4, 8) and once at the end of the trial (month 12))
  • Pupal indices: pupae per person index, pupa index and pupae per hectare index(Before (month 1), twice during (month 4, 8) and once at the end of the trial (month 12))
  • Adults: parity rate(Continuously during months 1-4 (baseline) and months 5-17 (trial))
  • Knowledge, attitudes, and practices on Dengue prevention among the population of Cocody-Bingerville(Before (month 1) the start of the trial and at the end of the trial (month 12))
  • Mapping and describe Aedes aegypti breeding sites, focusing on their geographic and ecological characteristics. This mapping will be used to enhance targeted larval control efforts in these areas.(Before (month 1) the start of the trial and at the end of the trial (month 12))
  • Container index(before (month 1), twice during (month 4, 8) and once at the end of the trial (month 12))
  • Breteau index(Before (month 1), twice during (month 4, 8) and once at the end of the trial (month 12))

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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