Pilot study to determine photoreceptor contribution to Non-Image Forming effects

Completed

• Conditions: Daytime pupil response and alertness; photoreceptor adaptation; pupil response

• Registration Number: NL-OMON42603
• Lead Sponsor: Rijksuniversiteit Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 16

Inclusion Criteria

healthy men and women (18-30 y)
normal chronotype
normal sleep duration
women using a hormonal form of birth control (steady hormone levels)

Exclusion Criteria

short (<6.5h) or long sleeper (>9h)
going out more than two nights a week until minimally 7AM
extreme early or late chronotype
chronic (psychiatric or somatic) disease
sleep disorder
eye complaints or eye surgery in the past (excluding use of contact lenses)
use of chronic (photosensitizing) medication in 3 months prior to start of stydt
regulary use of sleep medication or stimulating drugs
colour blindness
more than 3 glasses of alcohol on working days, and or the regularly use of drugs
more than 8 caffeinated drinks per day
regularly napping (more than 2 times a week)
shiftwork in 3 months prior to the start of the study
travelled across more than 1 timezone in the month prior to the start of the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Pupillary unrest index, pupil response (constriction and adaptation during<br /><br>exposure to light)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n.a.</p><br>