Respiratory Management of Preterm Infants and Bronchopulmonary Dysplasia
- Conditions
- Bronchopulmonary Dysplasia
- Registration Number
- NCT03411018
- Lead Sponsor
- Manuel Sanchez Luna
- Brief Summary
This observational study evaluates the impact of respiratory management modifications implemented in our institution on the intubation rates and the death or Bronchopulmonary Dysplasia (BPD) outcome.
- Detailed Description
Less invasive respiratory management has been implemented in most neonatal units as well as lung protective ventilatory strategies when intubation is required in order to minimize ventilator induced lung injury.
In our institution a new ventilatory protocol including less invasive surfactant administration, Synchronized nasal positive pressure ventilation and early rescue High frequency ventilation has been implemented during 2013-14.
Hypothesis: New less invasive and lung protective strategies to prevent lung injury had been effective in reducing intubation rates.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 600
All preterm Infants born with less than 32wGA admitted in our NICU.
Congenital malformations and Known Chromosomal disorders,
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BRONCHOPULMONARY DySPLASIA 36 weeks of postmenstrual age. Diagnosis of moderate-severe bronchopulmonary dysplasia (physiological definition)
mortality before discharge death
- Secondary Outcome Measures
Name Time Method Mechanical ventilation during hospitalization requirement of mechanical ventilation
Trial Locations
- Locations (1)
Cristina Ramos-Navarro
🇪🇸Madrid, Spain
Cristina Ramos-Navarro🇪🇸Madrid, Spain