Evaluating nasal sprays and physical activity/stress management in reducing respiratory infections in primary care

Not Applicable

• Conditions: Respiratory tract infections; Respiratory

• Registration Number: ISRCTN17936080
• Lead Sponsor: niversity of Southampton

Brief Summary

2023 Protocol article in https://pubmed.ncbi.nlm.nih.gov/37450460/ (added 17/07/2023) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/39004091/ (added 16/07/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-30
• Last Update Posted: 29 July 2024
• Study Completion: 2024-10-01

Recruitment & Eligibility

• Status: Ongoing
• Sex: All
• Target Recruitment: 13799

Inclusion Criteria

1. Patients aged =18 years with a risk factor:
1.1. Known weakened immune system due to a serious illness or medication (e.g. chemotherapy)
1.2. Known heart disease
1.3. Known asthma or lung disease
1.4. Known diabetes
1.5. Known mild hepatic impairment
1.6. Known stroke or neurological problem
1.7. Obesity (BMI >30)
1.8. Patients with =3 episodes of an RTI in the last year
2. Patients aged =65
3. Have access to the internet

Exclusion Criteria

1. Terminal illness/palliative care
2. Living with dementia
3. Living in residential care
4. Pregnancy or breastfeeding
5. Regular use of nasal sprays for respiratory infection control in the last 6 months
6. Allergy to nasal sprays
7. Living in the same household as another participant
8. Previously involved in RECUR programme development work

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of illness due to respiratory tract infections (RTIs) measured using patient report of total days with symptoms over 6 months (data collected monthly, at 3, 6 and 12 months)