Clinical trial on the effectiveness of the Famotidine on symptoms of schizophrenic patients
Phase 3
- Conditions
- Schizophrenia.Schizophrenia
- Registration Number
- IRCT20190707044123N1
- Lead Sponsor
- Rasht University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 64
Inclusion Criteria
The diagnosis of schizophrenia based on Diagnostic and Statistical Manual of Psychiatric Disorders (DSM5)
Patients receiving second-generation drugs
A year past diagnosis of schizophrenia
Patients have a secondary school education
Exclusion Criteria
Sensitivity to famotidine
Drug abuse
Serious medical illness (Nephrology disease)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Symptoms of schizophrenia. Timepoint: The effectiveness of the treatment will be evaluated in Baseline and Six weeks after the intervention. Method of measurement: The effectiveness of the treatment will be evaluated in Baseline and Six weeks after the intervention based on the score obtained from the Wechsler Memory Scale(WMS) and Positive and Negative Symptoms of Schizophrenia(PANSS).
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie Famotidine's antipsychotic effects in schizophrenia via H2 receptor antagonism?
How does Famotidine compare to standard antipsychotics like risperidone in Phase III trials for schizophrenia symptom reduction?
Are COMT or BDNF polymorphisms predictive of Famotidine response in IRCT20190707044123N1 schizophrenia patients?
What adverse events are reported with Famotidine in schizophrenia populations versus traditional antipsychotic therapies?
What combination therapies with H2 antagonists show promise in treating treatment-resistant schizophrenia subtypes?