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Clinical Trials/NCT06218355
NCT06218355
Recruiting
Not Applicable

IMPACT: Improving Maternal Postpartum Access to Care Through Telemedicine

University of Texas Southwestern Medical Center2 sites in 1 country3,500 target enrollmentMarch 1, 2024

Overview

Phase
Not Applicable
Intervention
Intensive Education
Conditions
Postpartum Complication
Sponsor
University of Texas Southwestern Medical Center
Enrollment
3500
Locations
2
Primary Endpoint
Composite Healthcare Outcome - time to diagnosis and treatment of postpartum complications after hospital discharge
Status
Recruiting
Last Updated
last month

Overview

Brief Summary

The purpose of this study is to compare two complex, multi-component evidence-based postpartum interventions in underserved populations of lower socioeconomic status in an effort to reduce maternal morbidity and mortality.

Detailed Description

This large, multi-center randomized controlled trial will compare two multi-component postpartum care models via hybrid type 1 design conducted in two phases. An initial phase (phase 1) will collect baseline data and ensure patient input into final study. In phase 2, women will be randomized. Comparators are evidenced- based approaches: (1) an intensive in-person education with virtual education via push notifications using an electronic health record web portal; (2) a telehealth model using serial encounters. The "push" approach using notifications directly contrasts with the "pull" approach using telehealth visits. Both models include home visit programs. The study population includes patients delivering in two urban, inner-city health systems: Parkland (Dallas, TX) and Grady Memorial (Atlanta, GA). The primary outcome is time from hospital discharge to diagnosis and treatment of a composite of complications in the first 6 weeks. Based upon pilot data, 2349 women will demonstrate a 40% reduction (9 to 5.4 days) with 80% power and two-sided alpha of 0.05. 3500 women will be enrolled (1000 in phase 1; 2500 in phase 2) with anticipated \<5% attrition at 6 weeks. Inclusion will be women who deliver liveborn infants. Secondary outcomes include mental health disorders, emergency room visits, hospital admissions, patient knowledge, quality of life and satisfaction, provider satisfaction, and social determinants of health. Women will be followed for one year postpartum.

Registry
clinicaltrials.gov
Start Date
March 1, 2024
End Date
September 1, 2028
Last Updated
last month
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Elaine Duryea

Associate Professor

University of Texas Southwestern Medical Center

Eligibility Criteria

Inclusion Criteria

  • Postpartum women who deliver a live born infant at Parkland Hospital or Grady Health and receive postpartum care at dedicated community clinics.
  • Due to the nature of the study, all will be women, and all will be postpartum, thus of reproductive age. Postpartum women 18 years of age and older will be considered for inclusion if informed consent can be obtained.

Exclusion Criteria

  • Postpartum women who do not deliver at Parkland Hospital or Grady Health will not receive postpartum care in the pre-specified community clinics for Parkland health systems.
  • Patients with a primary language other than English or Spanish.

Arms & Interventions

Intensive Education

Women enrolled in the intensive education care model participate in intensive in-person education as well as ongoing virtual education via the electronic health record web portal in the form of strategically timed "pushes" of relevant and digestible educational elements via a "Care Companion." These virtual education "pushes" will include "to do" list reminders to check vital signs and submit them for review to the care team. Positive reinforcement will be provided when tasks are completed.

Intervention: Intensive Education

Enhanced Virtual Care

Women in the enhanced virtual care model will receive scheduled telehealth visits on the platform of their choice - either via video or audio-only synchronous visits. Patients in the virtual care model will check vital signs with home devices during the telehealth visit and report them directly to the provider. This "pull" approach to data collection directly contrasts with the "push" approach of comparator #1.

Intervention: Enhanced Virtual Care

Outcomes

Primary Outcomes

Composite Healthcare Outcome - time to diagnosis and treatment of postpartum complications after hospital discharge

Time Frame: Up to one year postpartum

Time to diagnosis and treatment of postpartum complications including hypertension, wound infection, and venous thromboembolism, measured in days. Lower value is considered better, representing timely care.

Secondary Outcomes

  • PROMIS-29 questionnaire v 2.1(6 weeks and 1 year postpartum)
  • Systolic Blood Pressure(enrollment, 1 week, 6 weeks, 3 months, 6 months, 1 year postpartum)
  • Postpartum warning signs knowledge assessment, based on AWOHHN criteria(enrollment, 1 week, 6 weeks, 3 months, 6 months, 1 year postpartum)
  • Number of patients requiring emergency room visits, % preventable(Up to one year postpartum)
  • Healthy People 2030 questionnaire(6 weeks and 1 year postpartum)
  • PRAPARE questionnaire(6 weeks and 1 year postpartum)
  • Provider Satisfaction Survey (Quantitative)(Every 6 months throughout the study period)
  • Social Determinants of Health - Healthy People 2030 and PRAPARE questionnaire(enrollment, 6 weeks, 1 year postpartum)
  • Long-term disease control - diabetes - hemoglobin A1c, LDL, HDL, total cholesterol, triglycerides(enrollment, 6 weeks, 3 months, and 1 year postpartum)
  • Long-term disease control - anemia - hemoglobin and hematocrit(enrollment, 6 weeks, 3 months, and 1 year postpartum)
  • Edinburgh Postnatal Depression Scale(enrollment, 1 week, 6 weeks, 3 months, 6 months, 1 year postpartum)
  • Generalized Anxiety Disorder 7(enrollment, 1 week, 6 weeks, 3 months, 6 months, 1 year postpartum)
  • Number of patients requiring hospital admissions, % preventable(Up to one year postpartum)
  • Diastolic Blood Pressure(enrollment, 1 week, 6 weeks, 3 months, 6 months, 1 year postpartum)
  • Long-term disease control - hypertension - serum creatinine(enrollment, 6 weeks, 3 months, and 1 year postpartum)
  • Short Assessment of Patient Satisfaction (SAPS)(6 weeks and 1 year postpartum)
  • Long-term disease control - liver function test (AST, ALT)(enrollment, 6 weeks, 3 months, and 1 year postpartum)

Study Sites (2)

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