Acute alvleesklierontsteking van onbekende oorzaak: de rol van een inwendige echo in het vaststellen van een oorzaak
- Conditions
- PancreatitisAcute pancreatitisIdiopathic pancreatitisIdiopathische pancreatitisIdiopathic acute pancreatitis Idiopathische acute pancreatitis Endoscopic ultrasonographyEndoscopic ultrasoundEndo-echoEndoscopische echografieEndoscopische echo AetiologyEtiologyEtiologie
- Registration Number
- NL-OMON25133
- Lead Sponsor
- Prof. Dr. P. Fockens, MD, PhD Head of department Department of Gastroenterology & HepatologyC2-330 Academic Medical Center Meibergdreef 9 1105 AZ, Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 106
Inclusion Criteria
1. Patients older than 18 years
2. First episode of idiopathic acute pancreatitis
Exclusion Criteria
1. Patients in whom an aetiology is found in standard work-up
2. Diagnosis of chronic pancreatitis (according to the M-ANNHEIM classification) in standard work-up
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The amount of patients with idiopathic acute pancreatitis in whom endoscopic ultrasound detects gallstone disease or other causes of pancreatitis (such as chronic pancreatitis or pancreatic tumours).<br><br /><br /><br>Positive imaging is defined as imaging during which a definitive cause for the acute pancreatitis episode can be found; or during which abnormalities are visualized in which, after obtaining tissue and pathological examination, pathological tissue is found.
- Secondary Outcome Measures
Name Time Method 1. Recurrence rate of acute pancreatitis in endoscopic ultrasound-negative” idiopathic acute pancreatitis <br /><br>2. Severity of recurrent pancreatitis (according to the revised Atlanta classification)<br /><br>3. Readmission<br /><br>4. Additional invasive interventions:<br /><br> a. Cholecystectomy<br /><br> b. Endoscopic sphincterotomy<br /><br>5. Complications of interventions, according to the Clavien-Dindo classification <br /><br> a. Endoscopic procedures: perforation, bleeding, cholangitis, post-procedure pancreatitis, infection (defined as fever and bacteraemia), sedation-related complications or other complications <br /><br> b. Cholecystectomy: perforation, bleeding, bile duct injury, infection (defined as fever and positive blood, wound or specimen culture), sedation-related complications or other complications <br /><br>6. Length of hospital stay<br /><br>7. Quality of life<br /><br>8. Mortality<br /><br>9. Costs