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Epiglottic Downfolding During Endotracheal Intubation

Not Applicable
Withdrawn
Conditions
Injury of Epiglottis
Intubation Complication
Interventions
Device: C-MAC® videolaryngoscope (Karl Storz, Tuttlingen, Germany)
Registration Number
NCT01691963
Lead Sponsor
Catharina Ziekenhuis Eindhoven
Brief Summary

Usually videolaryngoscopy using a videolaryngoscope with a classic Macintosh design is performed with the blade in the vallecula and the epiglottis elevated from the vocal cords indirectly, as in direct laryngoscopy. However, during an audit of videolaryngoscopic practice we noticed that, in obtaining the best view, clinicians frequently and inadvertently advanced the blade into the vallecula to get a better view, such that the epiglottis was downfolded and elevated directly from the vocal cords. However, a better view does not necessarily lead to higher intubation success.

In this randomized, controlled trial, we want to determine the efficacy of videolaryngoscope-guided tracheal intubation using an alternative position for the blade in patients with normal airways.

Detailed Description

Anaesthesia will be induced in the conventional matter. For patients randomized to the intervention group, when the anaesthesiologist considers the depth of anaesthesia to be sufficient, a C-MAC® videolaryngoscope (Karl Storz, Tuttlingen, Germany), will be placed into the patients mouth. The best possible view of the vocal cords will be obtained with the blade positioned normally in the vallecula anterior to the epiglottis. The epiglottis will be elevated from the vocal cords indirectly, identical with direct laryngoscopy. After this, the best possible view of the vocal cords will be obtained with the blade positioned alternatively in the vallecula posterior to the epiglottis, such that the epiglottis is downfolded and elevated directly from the vocal cords. Views will be scored in both positions using the Cormack and Lehane classification system. When correct laryngoscope positioning can't be achieved with a size 3 blade, a size 4 blade will be used.

For patients not randomized to the intervention group, anaesthesia will also be induced in the conventional matter. When the anaesthesiologist considers the depth of anaesthesia to be sufficient, a C-MAC® videolaryngoscope (Karl Storz, Tuttlingen, Germany), will be placed into the patients mouth. The best possible view of the vocal cords will be obtained with the blade positioned normally in the vallecula anterior to the epiglottis. The epiglottis will be elevated from the vocal cords indirectly, identical with direct laryngoscopy. The view will be scored in this position using the Cormack and Lehane classification system. After this, the patient will be intubated.

Patients will be interviewed 2 and 24 hours postoperatively about sore throat, dysphonia, dysphagia and coughing.

Recruitment & Eligibility

Status
WITHDRAWN
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • Informed patient consent
  • ASA I-III
  • Age > 18 years
  • Elective surgery, other than head and/or neck surgery
  • Elective surgery, duration < 1 hour in supine position
  • Pre-operative Mallampati I-II-III
Exclusion Criteria
  • No informed patient consent
  • ASA IV
  • Age < 18 years
  • Preoperative complaints of sore throat, dysphagia, dysphonia and coughing
  • Emergency surgery, surgery of head and/of neck
  • Surgery during > 1 hour in other than supine position
  • Locoregional anaesthesia
  • Preoperative Mallampati IV
  • Known difficult airway
  • Bad dentition
  • Dental crowns and/or fixed partial denture
  • Risk of aspiration (fasted < 6 hours, gastroesophageal reflux)

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Epiglottic downfoldingC-MAC® videolaryngoscope (Karl Storz, Tuttlingen, Germany)Endotracheal intubation will be achieved using a C-MAC® videolaryngoscope (Karl Storz, Tuttlingen, Germany) with a size 3 Macintosh blade. The best possible view of the glottic inlet will be scored with the blade tip positioned in the vallecula. Next, the view of the glottic inlet will be scored with the blade advanced further into the vallecula, until the epiglottis flips infero-posteriorly and becomes downfolded into the trachea. The glottic view will be scored in both positions using the Cormack and Lehane classification system. After successful intubation, the blade will slowly be withdrawn into the vallecula to elevate the epiglottis back to its normal position.
Primary Outcome Measures
NameTimeMethod
The Cormack and Lehane gradePatients will be followed for the duration of induction of anaesthesia, an average of 10 minutes

The Cormack and Lehane grade scored in both positions of the C-MAC® videolaryngoscope and consequent success of intubation

Secondary Outcome Measures
NameTimeMethod
Use of adjunctsPatients will be followed for the duration of induction of anaesthesia, an average of 10 minutes

Frequency of use of a stylet, gum elastic bougie or BURP manoeuvre.

DiscomfortPatients will be followed for 24 hours postoperatively

Sore throat, dysphonia, dysphagia and coughing reported by patients 2 and 24 hours postoperatively

Trial Locations

Locations (1)

Catharina Ziekenhuis Eindhoven

🇳🇱

Eindhoven, Netherlands

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