Acute effects of high-protein and high-fat oral preloads on thermogenesis, appetite perceptions and energy intake, and the relationship with antropyloroduodenal motility, gastric emptying and gut hormone release, in overweight men.

Professor Christine Feinle-Bisset0 个研究点目标入组 16 人开始时间: 2011年9月1日最近更新: 2020年1月13日

适应症

试验速览

暂无简介。

•16 overweight/obese (BMI 27-35kg/m2) subjects will be recruited. All subjects will be required to be weight-stable (i.e. <5% fluctuation in their body weight) at study entry. Subjects will be requried to maintain their normal physical activity over the course of the study.

•Significant gastrointestinal symptoms, disease or surgery, use pf prescription or non-prescription medications (including vitamins and herbal suppliments) which may affect energy metabolism, gastrointestinal function, body weight or appetite (eg. domperidone and cisapride, anticholinergic drugs (ag. atropine), metoclopramide, erythromycin, hyoscine, orlistat, geren tea extracts, Astragalus, St Johns Wort etc), intolerance /allergy to paracetamol, current gallbladder or pancreatic disease, diabetes mellitus, epilepsy, cardiovascular or respiratory disease, any other illness as assessed by the investigator (including chronic illnesses not explicitly listed above), high performance athletes, current intake of >2 standard drinks on >5 days per week, curent smokers of cigarettes/cigars/marijuana, current intake of any illicit substances, restrained eaters (score > 12 on the three factor eating questionnaire), experience claustrophobis in confined spaces, or unable to comprehend the study protocol.

发起方

Professor Christine Feinle-Bisset