PERIOPERATIVE ANALGESIC STRATEGIES IN PAEDIATRIC LIVER TRANSPLANT RECIPIENTS
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To determine the requirement of perioperative opioids in paediatric liver transplant recipients
研究概览
简要总结
Pain score will be assessed using the following age appropriate scales
Assessment will be done by independent assessors using dedicated scores.
Peak pain score, total dosage of dexmedetomidine and opioids, average duration of analgesic requirement and details of rescue drugs with dosages used will be recorded during the study period.
Complications such as hemodynamic changes requiring dose modifications or discontinuation of drugs, gastrointestinal symptoms such as nausea, vomiting, constipation, ileus will be recorded.
Vomiting will be recorded at 24, 48, 72 hours as per vomiting score (0: no nausea, no vomiting; 1: nausea alone; 2: one episode of emesis; and 3: two or more episodes of emesis)
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Day(s) 至 18.00 Year(s)（—）
- 性别
- All
入选标准
- •All paediatric liver transplant recipients undergoing liver transplantation.
排除标准
- •Patients not willing for participation Multiorgan transplantation Re-exploration on Postoperative day 3 and beyond Re-intubation on postoperative day 3 and beyond.
结局指标
主要结局
To determine the requirement of perioperative opioids in paediatric liver transplant recipients
时间窗: Postoperative Day 0 to day 3 after liver transplant surgery
次要结局
- To determine the need for the first rescue analgesic in the postoperative period(In the first 3 days following liver transplantation)
研究者
Susan Paulin
Dr Rela Institute And Medical Centre