Medial Border of Laparoscopic D3 Lymphadenectomy for Right Colon Cancer

Withdrawn

• Conditions: Colon Cancer
• Interventions: Procedure: medial border along the left side of SMV; Procedure: medial border along the left side of SMA

• Registration Number: NCT04518449
• Lead Sponsor: Shanghai Minimally Invasive Surgery Center

Brief Summary

This study investigats the gastrointestinal functional outcomes of laparoscopic D3 lymphadenectomy for right colon cancer with the medial border along the left side of superior mesenteric artery (SMA) versus the left side of superior mesenteric vein (SMV). This is a single center, prospective cohort study with a sample size of 264 patients. The primary endpoint is the incidence of diarrhea (evaluated using the Diarrhea Assessment Scale) one month after surgery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-08-16
• Study First Submitted QC: 2020-08-16
• Study First Posted: 2020-08-19
• Study Start: 2022-12-01
• Primary Completion: 2023-10-31
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-22
• Last Update Posted: 2024-02-26
• Study Completion: 2025-10-31

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• Age between 18 and 75 years
• American Society of Anesthesiologists (ASA) score I to III
• A biopsy proven histological diagnosis of colorectal carcinoma
• tumor located at right half of colon
• Undergoing laparoscopic right hemi-colectomy
• preoperative staging cT2-4aN0M0 or cTanyN+M0
• willing to participate and informed consent signed

Exclusion Criteria

• Pregnant or lactating women
• Synchronous colorectal carcinoma
• History of colorectal cancer or other malignant tumors
• Clinical evidence of metastasis
• Preoperative staging cT1N0 or cT4bNany
• Emergency procedure

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
SMV group	medial border along the left side of SMV	the medial border along the left side of superior mesenteric vein (SMV)
SMA group	medial border along the left side of SMA	the medial border along the left side of superior mesenteric artery (SMA)

Primary Outcome Measures

Name	Time	Method
incidence of diarrhea	one month after surgery	Diarrhea Assessment Scale: stool score ≥ 5