NCT05992987尚未招募不适用
Assessment of Serum Levels of Adenosine Deaminase and Immunoglobulin E in Patients With Chronic Spontaneous Urticaria
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 主要终点
- Serum level of IgE
研究概览
简要总结
adenosine deaminase activity (ADA) has been reported to be elevated in various diseases such as psoriasis, acne and juvenile idiopathic arthritis. There is no previous studies that assessed ADA in chronic spontaneous urticaria (CSU) .
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients complaining of CSU and a group of age and sex-matched healthy controls (blood donors).
排除标准
- •Pregnancy and lactation.
- •Patients with systemic diseases, especially those with autoimmune diseases and infections.
- •Patients with skin diseases.
- •Patients on medications such as antibiotics, nonsteroidal anti-inflammatory drugs, angiotensin-converting enzyme inhibitors, anticonvulsants, penicillin, and combined oral contraceptives.
结局指标
主要结局
Serum level of IgE
时间窗: 3 months
Difference in serum level of IgE between CSU group and control group
Serum level of adenosine deaminase
时间窗: 3 months
Difference in serum level of adenosine deaminase between CSU group and control group
次要结局
未报告次要终点
研究者
Ahmed Mohamed Ahmed
Resident physician at Dermatology department, Sohag University
Sohag University
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