NCT05992987
Not yet recruiting
Not Applicable
Assessment of Serum Levels of Adenosine Deaminase and Immunoglobulin E in Patients With Chronic Spontaneous Urticaria
ConditionsChronic Spontaneous Urticaria
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Spontaneous Urticaria
- Sponsor
- Sohag University
- Enrollment
- 90
- Primary Endpoint
- Serum level of IgE
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
adenosine deaminase activity (ADA) has been reported to be elevated in various diseases such as psoriasis, acne and juvenile idiopathic arthritis. There is no previous studies that assessed ADA in chronic spontaneous urticaria (CSU) .
Investigators
Ahmed Mohamed Ahmed
Resident physician at Dermatology department, Sohag University
Sohag University
Eligibility Criteria
Inclusion Criteria
- •adult patients complaining of CSU and a group of age and sex-matched healthy controls (blood donors).
Exclusion Criteria
- •Pregnancy and lactation.
- •Patients with systemic diseases, especially those with autoimmune diseases and infections.
- •Patients with skin diseases.
- •Patients on medications such as antibiotics, nonsteroidal anti-inflammatory drugs, angiotensin-converting enzyme inhibitors, anticonvulsants, penicillin, and combined oral contraceptives.
Outcomes
Primary Outcomes
Serum level of IgE
Time Frame: 3 months
Difference in serum level of IgE between CSU group and control group
Serum level of adenosine deaminase
Time Frame: 3 months
Difference in serum level of adenosine deaminase between CSU group and control group
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