EUCTR2020-002952-18-GB进行中（未招募）1 期
Targeting de novo Pyrimidine Biosynthesis by leflunomide as a Novel Concept for the Treatment of Corona Virus Disease 2019 (COVID-19) - DEFEAT- Covid Study
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 入组人数
- 178
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1. Age =18 years
- •2. Patients with onset of symptoms ?15 days of onset
- •3. Laboratory (RT-PCR) confirmed infection with 2019-nCoV.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range: 0
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 0
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 0
排除标准
- •1. Pregnant or breast-feeding women;
- •2. Individuals already receiving specific antiviral medications (such as lopinavir/lidonavir, ribavirin), monoclonal antibodies, or other drug trial treatment for COVID-19 within one week prior to study enrolment;
- •3. Liver function tests>2 fold of upper limits of normal (ULN).
- •If the attending clinician considers that there exists a specific contra-indication to leflunomide (such as severe hypoproteinaemia, severe immunodeficiency) to Leflunomide, then the patient would be considered ineligible for the study
研究者
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