NL-OMON49970尚未招募不适用
Improving the safety of fluoropyrimidine-based chemotherapy by combined DPYD genotype-guided and DPD phenotype-guided dose individualisation: The Alpe2U study - Improving the safety of fluoropyrimidine-based chemotherapy
Antoni van Leeuwenhoek Ziekenhuis0 个研究点目标入组 1,440 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 1,440
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. Pathologically confirmed malignancy for which treatment with a
- •fluoropyrimidine is considered to be in the patient*s best interest
- •2. Patient need to be of Western descent
- •3. Age >= 18
- •4. Able and willing to give written informed consent
- •5. WHO performance status of 0, 1 or 2
- •6. Able and willing to undergo extra blood sampling for study related analysis
- •7. Adequate baseline patient characteristics (complete blood count, hepatic
- •function which involves serum bilirubin, AST, ALT, and renal function)
排除标准
- •1. Prior treatment with fluoropyrimidines
- •2. Patients with known substance abuse, psychotic disorders, and/or other
- •diseases expected to interfere with study or the patient*s safety
- •3. Patients treated with the combination of a fluoropyrimidine and irinotecan
研究者
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