ACTRN12612000055808
Recruiting
Phase 4
Efficacy and safety of topical corticosteroid compared to placebo in the treatment of bacterial keratitis
niversity of Auckland0 sites144 target enrollmentJanuary 11, 2012
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Bacterial keratitis
- Sponsor
- niversity of Auckland
- Enrollment
- 144
- Status
- Recruiting
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of culture postivie bacterial keratitis, corneal defect less than or equal to 1\.5mm and not within 1\.0mm of the limbus, aged 16 or over, topical antibiotic given for at least three days with signs of clinical improvement.
Exclusion Criteria
- •Corneal perforation or impending perforation, descemetocele or endophthalmitis, evidence of herptic keratitis, fungal, or acanthambeoba infection by exam or history, pre\-existing corneal scar, use of topical steriod in affected eye or systemic corticosteriod during course of present infection, aged under 16 years, bilateral corneal infections, previous penetrating corneal transplant, pregnancy, best corrected vision worse than 6/60 in fellow eye, allergy to study drugs, uncontrolled systemic disease, concurrent ocular infections and patients requiring treatment with subconjuctival injection.
Outcomes
Primary Outcomes
Not specified
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