CTRI/2013/01/003286
Completed
未知
CLINICAL AND RADIOGRAPHIC ASSESSMENT OF BONE REGENERATION USING ALENDRONATE SODIUM GEL AS ANADJUNCT TO SURGICAL THERAPY FOR THE TREATMENT OF OSSEOUS DEFECTS IN CHRONIC PERIODONTITIS- A COMPARATIVE STUDY
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- PRINCIPAL INVESTIGATOR
- Enrollment
- 30
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •a)Patient of either sex within the age group of 35\-50 years.
- •b)Systemically healthy patients.
- •c)Clinical diagnosis of moderate generalized chronic periodontitis.
- •d)Patients with probing depth \>\=5 mm or clinical attachment loss \> 4 to 6 mm bilaterally as evidenced by clinical examination.
- •e)Patients with vertical bone loss \> 5mm as evidenced on IOPA radiograph.
- •f)Patients with acceptable oral hygiene following Phase\-I therapy.
Exclusion Criteria
- •a)Patients with presence of systemic conditions or disease affecting bone density e.g. Osteoporosis, Pagetâ??s disease.
- •b)Patients with known or suspected allergy to Alendronate/ bisphosphonates group.
- •c)Patients with Aggressive Periodontitis.
- •d)Patients with horizontal bone loss.
- •e)Patients without any contradictions for periodontal surgery.
- •f)Patients with a history of drug intake that can affect bone metabolism in the past 6 months. E.g. NSAIDs.
- •g)Patients who are current smokers, or ex smokers for less than five years.
- •h)Pregnant or lactating females.
- •i)Patients who are alcoholics.
- •j)Immunocompromised patients.
Outcomes
Primary Outcomes
Not specified
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