CLINICAL AND RADIOGRAPHIC ASSESSMENT OF BONE REGENERATION USING ALENDRONATE SODIUM GEL AS ANADJUNCT TO SURGICAL THERAPY FOR THE TREATMENT OF OSSEOUS DEFECTS IN CHRONIC PERIODONTITIS- A COMPARATIVE STUDY

PRINCIPAL INVESTIGATOR0 个研究点目标入组 30 人开始时间: 待定最近更新: 2021年11月24日

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•a)Patient of either sex within the age group of 35-50 years.
•b)Systemically healthy patients.
•c)Clinical diagnosis of moderate generalized chronic periodontitis.
•d)Patients with probing depth >=5 mm or clinical attachment loss > 4 to 6 mm bilaterally as evidenced by clinical examination.
•e)Patients with vertical bone loss > 5mm as evidenced on IOPA radiograph.
•f)Patients with acceptable oral hygiene following Phase-I therapy.

•a)Patients with presence of systemic conditions or disease affecting bone density e.g. Osteoporosis, Pagetâ??s disease.
•b)Patients with known or suspected allergy to Alendronate/ bisphosphonates group.
•c)Patients with Aggressive Periodontitis.
•d)Patients with horizontal bone loss.
•e)Patients without any contradictions for periodontal surgery.
•f)Patients with a history of drug intake that can affect bone metabolism in the past 6 months. E.g. NSAIDs.
•g)Patients who are current smokers, or ex smokers for less than five years.
•h)Pregnant or lactating females.
•i)Patients who are alcoholics.
•j)Immunocompromised patients.
•k)Patients using tobacco in any form.
•l)Patients with gross oral pathology, tumors which can alter the course of periodontal
•m)Patients who have taken medications affecting periodontal status or has received periodontal therapy in the preceding six months.

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