Prognostic Evaluations of Ketohexokinase Isoforms in Endometrial Cancer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 220
- 试验地点
- 1
- 主要终点
- The role of ketohexokinase isoforms in the overall survival of endometrial cancer.
研究概览
简要总结
Our preliminary analysis with clinical database suggested that, in patients with type I endometrial cancer, high ketohexokinase-expressing group have lower survival probabilities than low ketohexokinase-expressing group. To understand the importance of ketohexokinase expression and isoform switch during the development of type I endometrial cancer, we propose a series of in vitro experiments and clinical examinations in this project.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 —(Adult, Older Adult)
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •>20 years
- •Women with endometrial cancer who are about to be admitted to hospital for gynecological staging.
- •Women who have undergone gynecological staging surgery for endometrial cancer in the past.
排除标准
- •Women with endometrial cancer who receive preoperative chemotherapy or radiation therapy.
结局指标
主要结局
The role of ketohexokinase isoforms in the overall survival of endometrial cancer.
时间窗: 5 years
Cox proportional hazard regression to evaluate the role of ketohexokinase isoforms in the overall survival of endometrial cancer.
次要结局
- Correlation of ketohexokinase isoforms with the other prognostic risk factors(5 years)
研究者
Sheng-Mou Hsiao
Chief, Department of Obstetrics & Gynecology
Far Eastern Memorial Hospital
