跳至主要内容
临床试验/NCT03931265
NCT03931265招募中不适用

Prognostic Evaluations of Ketohexokinase Isoforms in Endometrial Cancer

Far Eastern Memorial Hospital1 个研究点 分布在 1 个国家目标入组 220 人开始时间: 2019年4月11日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
220
试验地点
1
主要终点
The role of ketohexokinase isoforms in the overall survival of endometrial cancer.

研究概览

简要总结

Our preliminary analysis with clinical database suggested that, in patients with type I endometrial cancer, high ketohexokinase-expressing group have lower survival probabilities than low ketohexokinase-expressing group. To understand the importance of ketohexokinase expression and isoform switch during the development of type I endometrial cancer, we propose a series of in vitro experiments and clinical examinations in this project.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • >20 years
  • Women with endometrial cancer who are about to be admitted to hospital for gynecological staging.
  • Women who have undergone gynecological staging surgery for endometrial cancer in the past.

排除标准

  • Women with endometrial cancer who receive preoperative chemotherapy or radiation therapy.

结局指标

主要结局

The role of ketohexokinase isoforms in the overall survival of endometrial cancer.

时间窗: 5 years

Cox proportional hazard regression to evaluate the role of ketohexokinase isoforms in the overall survival of endometrial cancer.

次要结局

  • Correlation of ketohexokinase isoforms with the other prognostic risk factors(5 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Sheng-Mou Hsiao

Chief, Department of Obstetrics & Gynecology

Far Eastern Memorial Hospital

研究点 (1)

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