A study to check whether addition of Resveratrol is beneficial and safe in patients with Diabetes, Dyslipidemia and Hypertension (who are already on standard therapy)
- Conditions
- Health Condition 1: null- Dyslipidemia, Diabetes and hypertension
- Registration Number
- CTRI/2017/04/008384
- Lead Sponsor
- Rakesh Ojha
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 180
Diabetes study:
Patients of either gender with known T2DM, aged between 20 and 65 years
Patient with borderline blood lipid abnormality and not taking any hypolipidemic agents
Patient is on stable monotherapy of Glimeperide 2 mg
Patient willing to use Plant based therapy (RESVERATROL) with gold standard therapy in management of their T2DM.
Dylipidemia study:
Patients with either sex in the age group of 20-65 years suffering from dyslipidemia
Patient who are on stable therapy of Atorvastatin 10 mg tablet
Patient willing to use Plant based therapy (RESVERATROL) with gold standard therapy (Statin) in management of dyslipidemia.
Hypertension study:
Patients of either sex, aged 20-65 yrs
Patients with Stage I hypertension (SBP 140â??159 mmHg and DBP 90â??99 mmHg)
Patients taking monotherapy of Telmisartan 20 mg
Patient willing to use Plant based therapy (RESVERATROL) with gold standard therapy (Telmisartan 20 mg) in management of hypertension.
Diabetes study:
Patients who are willing to use other antioxidant supplementation rather than RESVERATROL
Patients with type 1 diabetes, pregnant women and lactating mothers
Patients with dyslipidemia and taking lipid lowering therapy including statin
Patients with history of severe heart disease, hepatic and renal dysfunction
Patients taking/requiring beta â?? blocker and any drug which produce hyperglycemia or hypoglycemia.
Patients with history of allergy with grapes and consume alcohol daily
Dylipidemia study:
Patients who are willing to use other antioxidant supplementation rather than RESVERATROL
Pregnant women and lactating mothers
Patients taking/requiring any drug which affect blood lipid level
Patients with history of diabetes, severe heart disease, hepatic and renal dysfunction
Patients with history of allergy with grapes and consume alcohol daily
Hypertension study:
Patients who are willing to use other plant based therapy rather than RESVERATROL
Patients taking/requiring any drug which affect blood pressure
Pregnant women and lactating mothers
Patients with history of severe heart disease, hepatic and renal dysfunction
Patients with history of allergy with grapes and consume alcohol daily
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change in blood sugar level (fasting and fed), lipid profile and SBP and DBP from baseline to end of study visit (12 month)Timepoint: At baseline and 12 month
- Secondary Outcome Measures
Name Time Method Change in blood sugar level (fasting and fed), lipid profile, Hemoglobin A1c and systolic and diastolic blood pressureTimepoint: Baseline, at the end of 3 month, 6 month and 9 month