A pilot study of healthy volunteers to compare the performance of standard nasal oxygen cannula at high flows with the Optiflow” high flow nasal oxygen (HFNO) system.
Not Applicable
- Conditions
- Problem: Perioperative Oxygen deliveryAnaesthesiology - Anaesthetics
- Registration Number
- ACTRN12618001367235
- Lead Sponsor
- Fiona Stanley Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot yet recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Participant to be an anaesthetist. Healthy, non pregnant volunteers. No significant organ impairment of any kind. Aged 18-65. BMI 18-29 kg/m2.
Exclusion Criteria
•Respiratory / airway disease.
•Coagulopathy / anticoagulation or anti-platelet therapy.
•History of severe epistaxis.
•History of diabetes mellitus.
•History of severe gastro-oesophageal reflux disease, hiatus hernia or previous gastro-oesophageal surgery.
•Pregnancy.
•Any displaced nasal injury or history of nasal congestion.
•Participants unable to give informed consent.
•No at-risk populations will be targeted for inclusion.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparing oxygen delivery via proprietary HFNO system and standard nasal cannula at high flow, measured in pO2. This will be measured via transcutaneous oximetry. Devices with this capability include the Perimed PeriFlux System 5000 tcpO2 monitor[It is anticipated that a plateau will be reached in <5mins based on prior studies<br>];Presence or absence of gastric insufflation, characterised by bubbles on gastric ultrasound.[This will be monitored using real time gastric ultrasound for the duration of the high flow oxygen therapy; eg 5 minutes in total.]
- Secondary Outcome Measures
Name Time Method