Embryo Development Measure Depending on the DNA Sperm Fragmentation
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Time of pronuclear appearance in hours.
研究概览
简要总结
The embryokinetics may be a new prognostic factor for choosing the human embryos with the highest implantation potential. In order to identify the factors that may affect the rate of embryo cleavage, there are many studies about morphokinetics and culture medium, oxygen tension, oocyte quality or type of medication used for ovarian stimulation. However there are no published data with respect to the influence of sperm DNA fragmentation in the embryo kinetic.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 36 Years 至 38 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients 36 to 38 years
- •Fresh sample semen
- •Minimum 6 oocytes
- •Semen sample with at least 5 million/ml and at least 30% of progressive motile sperm.
排除标准
- •Patients younger than 36 or older than 38 years old
- •Frozen semen sample
- •Less tan 6 oocytes.
- •Semen samples with less than 5 million / ml or less than 30% of motile sperm.
研究组 & 干预措施
MACS
Patients with MACS Selection
干预措施: MACS (Other)
结局指标
主要结局
Time of pronuclear appearance in hours.
时间窗: The mean time of appearance of pronuclei is 3.3951 hours in our patients. We are going to evaluate pronuclear appearence time in hours in our study groups
We want to study whether differences exist in the time of appearance of pronuclei in those embryos that derived from semen samples from the two study groups the minimum value of the difference to be detected; we said that about 3 hours apart.
次要结局
未报告次要终点
研究者
David Agudo Garcillan
PHD
IVI Madrid