Randomized control trial of increased dose therapy with Entecavir vursus combination therapy with Entecavir and Adefovir in CHB patients with inadequate nucleoside analogue therapy
Not Applicable
- Conditions
- Chronic hepatitis B
- Registration Number
- JPRN-UMIN000003982
- Lead Sponsor
- Hyogo College Of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1. Resistant to Entecavir 2. Intolerance to Entecavir 3. Pregnant, lactating women 4. Possibly pregnant women 5. Chronic kidney failure 6. Creatinine clearance of <=50 mL/ min 7. Severe heart diseases 8. Decompensated liver cirrhosis 9. Liver transplant patient 10. HIV/HBV superinfection
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of HBcrAg, HBsAg
- Secondary Outcome Measures
Name Time Method safety