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Clinical Trials/NCT04593095
NCT04593095
Completed
N/A

Nurturing and Quiet Intervention (NeuroN-QI) on Preterm Infants' Neurodevelopment and Maternal Stress and Anxiety: Protocol of a Pilot Randomized Clinical Trial

St. Justine's Hospital1 site in 1 country24 target enrollmentJune 1, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Neurodevelopment
Sponsor
St. Justine's Hospital
Enrollment
24
Locations
1
Primary Endpoint
Feasibility and acceptability of the NeuroN-QI and the study procedures as assessed by a self-completed questionnaire (mothers) and a logbook (RA)
Status
Completed
Last Updated
last year

Overview

Brief Summary

The current state of knowledge reveals that the development of the brain of preterm infants is influenced by specific neonatal experiences during hospitalization, such as environmental sensory stimulation (light and noise), as well as physical and emotional proximity to mothers. However, there is a lack of evidence regarding the benefits that could be associated with the combination of care interventions to improve the health outcomes of preterm infants and their mothers, and in particular the development of the brain of infants during their hospitalization in the neonatal unit. The aim of this pilot study is to assess the feasibility and acceptability of a developmental care intervention including periods of nurturing between mothers and their infant (skin-to-skin contact and auditory stimulation) to promote physical and emotional proximity and a quiet period (controlled light and noise levels and olfactory stimulation in incubators) and to estimate the effect of this intervention on infants' neurodevelopment as well as on maternal stress and anxiety.

Registry
clinicaltrials.gov
Start Date
June 1, 2021
End Date
June 1, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
St. Justine's Hospital
Responsible Party
Principal Investigator
Principal Investigator

Marilyn Aita

Associate Professor & Researcher

Université de Montréal

Eligibility Criteria

Inclusion Criteria

  • born between 26 and 316/7 WGA.
  • agree to do 4 SSC sessions/week with a 15-minutes period of auditory (reading) stimulation;
  • express breast milk for their infant;
  • speak, read, or write French or English.
  • have at least 6 months of work experience in a NICU;
  • speak and read French or English.

Exclusion Criteria

  • have birth defects or genetic disorders;
  • have an intraventricular hemorrhage \> grade II;
  • receive nasal respiratory support;
  • have been transferred from another hospital.
  • are \<18 years of age;
  • had a multiparous birth;
  • have a physical condition that does not allow SSC;
  • abuse substances or alcohol;
  • do not intend to breastfeed or give breastmilk.

Outcomes

Primary Outcomes

Feasibility and acceptability of the NeuroN-QI and the study procedures as assessed by a self-completed questionnaire (mothers) and a logbook (RA)

Time Frame: 1 year

questionnaire completed by mothers - each question treated separately (no total score) Log book completed by a research assistant

Secondary Outcomes

  • Estimated effects of NeuroN-QI on maternal stress as assessed by PSS:NICU(1 year)
  • Feasibility of the NeuroN-QI as assessed by a self-completed questionnaire(1 year)
  • Estimated effects of NeuroN-QI on infants' neurodevelopment as assessed using the General Movements Assessment (GMA)(1 year)
  • Estimated effects of NeuroN-QI on maternal anxiety as assessed by STAI-Y(1 year)
  • Acceptability of the NeuroN-QI as assessed by a self-completed questionnaire(1 year)
  • Estimated effects of NeuroN-QI on infants' neurodevelopment as assessed using the Assessment of Preterm Infants Behavior (APIB)(1 year)
  • Nurses' training needs about the NeuroN-QI as assessed by a self-completed questionnaire(1 year)

Study Sites (1)

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