SUPPORT-pVAD

Phase 4

Recruiting

• Conditions: Cardiogenic shock; D012770

• Registration Number: JPRN-jRCT1061230015
• Lead Sponsor: Kazufumi Nakamura

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-05-20
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

1. 18 years-old or older
2. Signed and dated written informed consent
3. Cardiogenic shock
4. Supported with Impella 5.5, Impella CP
5. Indwelled with Pulmonary artery catheter

Exclusion Criteria

1. Using other mechanical circulatory support device except Impella 5.5 and Impella CP
2. Using nitroprusside, nitroglycerin, or sulfonamide
3. Pregnant or breastfeeding
4. Dependent on right to left shunt
5. Allergy to nitric oxide
6. Systolic blood pressure less than 90 mmHg
7. Judged as inappropriate by researchers

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of cardiac index ( LaFarge-Miettien fomula) from baseline to 15 minutes after intervention.

Secondary Outcome Measures

Name	Time	Method
1. change of mean pulmonary artery pressure<br>2. change of pulmonary vascular resistance<br>3. change of cardiac power output